To solve the problems and limitations in engineering design and practice ability of the chemical engineering undergraduates, School of Chemistry and Chemical Engineering, Hefei University of Technology, has focused on student-centered, ability-oriented and continuous improvement through the guidance of education accreditation. According to the core values of higher engineering education professional accreditation, we have deepened the reform and implemented the chemical design practical courses, and then integrated current teaching system, teaching objective and teaching model. It can be conductive to improve the professional literacy of students, the capacity of synthetically utilizing knowledge and the engineering consciousness.